Design, Fabrication, and Testing of a Chitosan Based Optical Biosensor:

This work presents the design, fabrication, and testing of an original concept for an optical biosensor device intended for use in a microfluidic network. The device uses planar waveguides intersecting a microfludic channel with biofunctionalized patterned sidewalls to detect biomolecules via fluorescent labeling. The optical-biological interface is provided through chitosan, a natural biopolymer. Chitosan is electrodepositable, and this material platform was developed to enable spatially selective and temporally selective assembly of biospecies in the sensor using electrical signals…

 

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